Involvement of USP24 in the DNA damage response

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Abstract

Deubiquitination has emerged as an important mechanism of regulating DNA repair pathways. We recently reported that USP24 is a novel p53 deubiquitinase that stabilizes p53 upon DNA damage. USP24 is upregulated by DNA damaging agents and plays an important role in maintaining genome stability.

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Zhang, L., & Gong, F. (2016). Involvement of USP24 in the DNA damage response. Molecular and Cellular Oncology, 3(1). https://doi.org/10.1080/23723556.2015.1011888

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