The role of Intralipid in prolonged parenteral nutrition. I. As a caloric substitute for glucose

Abstract

Three stable patients were studied in order to assess the role of intravenous fat solutions (Intralipid) in long term home parenteral nutrition. The standard source of nonprotein calories (NPC) in these patients was 60% glucose. Replacing 40% of NPC by Intralipid was effective in maintaining nitrogen balance and allowed total infusion time to be reduced from 12 hr to 8 hr. The serum triglyceride level was significantly elevated when glucose was used as the sole source of NPC, whereas serum cholesterol was significantly elevated when 40% of NPC were supplied by Intralipid.