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Journal ArticleOPEN ACCESS

Allelic Ratio of KRAS Mutations in Pancreatic Cancer

  • Lennerz J
  • Stenzinger A
The Oncologist (2015) 20(4) e8-e9
DOI: 10.1634/theoncologist.2014-0408
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Abstract

KRAS is not simply mutated or wild type in pancreatic ductal adenocarcinoma (PDAC); actually, it has never been. More than 90% of PDACs carry mutated KRAS alleles; however, the impact on PDAC biology may vary with the tumor-specific allelic ratio and dosage of mutated KRAS.

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Lennerz, J. K., & Stenzinger, A. (2015). Allelic Ratio of KRAS Mutations in Pancreatic Cancer. The Oncologist, 20(4), e8–e9. https://doi.org/10.1634/theoncologist.2014-0408

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