Unmasking connections in transmembrane immune signaling

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Abstract

The B cell transmembrane glycoprotein modulates immune signaling. Mice containing specific Cd22 mutations show that the extracellular glycan-binding function is regulatory and indicate unexpected complexity in CD22-ligand interactions.

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Marth, J. D. (2004, October). Unmasking connections in transmembrane immune signaling. Nature Immunology. https://doi.org/10.1038/ni1004-1008

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