Immunological aspects of patients infested with scabies in Thi-qar province, southern Iraq

Abstract

Scabies is skin disease of human and many mammalian hosts caused by the important obligate parasites Sarcoptes scabiei, lives and reproduces in epidermis, resulting a significant human and animal morbidity. The current study aimed to determine the immunological responses in patients infested with scabies who attended a private clinic in Al-Hussein general hospital in Thi-Qar province. The total white blood cell count, differential counts (lymphocytes, monocytes, neutrophils, eosinophils and basophils), the serum levels of IL-5 and IL-13 in were evaluated in all patients with scabies and compared with non-infested healthy individuals as a control group. The present study showed significant increase on the mean of total WBC in patients infested with scabies when compared with control (P≤ 0.05). A significant differences (P≤ 0.05) were recorded in the absolute leukocytes counts for patient infested with scabies when compared with control group except that for monocytes and basophils which were non-significant (P≤ 0.05) in our study. The results of study showed significant differences (P≤ 0.05) in the mean of IL-5 and IL-13 serum levels for the patient infested with scabies when compared with control.