Mediastinal endocrine neoplasm in patients with multiple endocrine adenomatosis. A previously unrecognized association

Abstract

Three cases of multiple endocrine adenomatosis (MEA) associated with a mediastinal endocrine neoplasm are presented. The mediastinal tumor was morphologically identical to the one described by us in 8 patients who did not have MEA. It behaved in an aggressive fashion and was the cause of death in all 3 cases. We regard this neoplasm as belonging to the family of carcinoid tumors and suggest an origin from the thymus gland. Copyright © 1972 American Cancer Society