Mild Cobalt(III)-Catalyzed Allylative C−F/C−H Functionalizations at Room Temperature

Abstract

Sustainable, cobalt-catalyst enabled, synthetically significant C−F/C−H functionalizations were achieved with an ample substrate scope at an ambient temperature of 25 °C, thereby delivering perfluoroallylated heteroarenes. Detailed experimental and computational mechanistic studies on the C−F/C−H functionalizations provided strong support for a facile C−F cleavage.