Antibiotic susceptibility patterns of respiratory isolates of Klebsiella pneumoniae in Europe and the USA in 1992 and 1993

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Abstract

The overall antibiotic susceptibility of Klebsiella pneumonias isolates collected in 1992 (n = 35) and 1993 (n = 85) was highly variable ranging from 0.8% for amoxycillin to 95.8% for ceftriaxone. On a weight for weight basis, the activity of the compounds decreased in the following sequence: ceftriaxone, cefixime, co-trimoxazole, ciprofloxacin, ofloxacin, cefaclor, amoxycillin/clavulanate, doxycycline, cefuroxime, chloramphenicol, amoxycillin. A small percentage of resistant strains was found for each of the compounds (between 0.8% for ceftriaxone and 12.5% for chloramphenicol) with the exception of amoxycillin which was almost uniformly resistant. There was a trend for the percentage of resistant strains to increase between the two study years for all compounds except for chloramphenicol. Resistance to β-lactams in France and the USA is likely to have been due to strains producing extended spectrum β-lactamases. © 1996 The British Society for Antimicrobial Chemotherapy.

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APA

Bauernfeind, A. (1996). Antibiotic susceptibility patterns of respiratory isolates of Klebsiella pneumoniae in Europe and the USA in 1992 and 1993. Journal of Antimicrobial Chemotherapy, 38(SUPPL. A), 107–115. https://doi.org/10.1093/jac/38.suppl_a.107

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