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Zoledronic acid for neonatal subcutaneous fat necrosis

  • Di Bari J
  • Nead J
  • Schurman S
Clinical Case Reports (2017) 5(5) 567-569
DOI: 10.1002/ccr3.855
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Abstract

Subcutaneous fat necrosis ( SFN ) in infants producing severe hypercalcemia is a life‐threatening emergency. Pathophysiology may include enhanced gastrointestinal calcium absorption and bone resorption. We treated an infant with SFN and serum calcium of 15 mg/dL with prednisolone and low‐dose zoledronic acid. Serum calcium promptly normalized without rebound hypocalcemia, and redosing of zoledronic acid was not necessary.

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Di Bari, J. A., Nead, J. A., & Schurman, S. J. (2017). Zoledronic acid for neonatal subcutaneous fat necrosis. Clinical Case Reports, 5(5), 567–569. https://doi.org/10.1002/ccr3.855

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