Insights into the Phytochemical and Pharmacological Natural Products of the Green Macroalga Halimeda (Chlorophyta)

Abstract

Our knowledge of the green macroalga Halimeda (Ulvophyceae, Chlorophyta) is still poor and underestimated from the phytochemical and pharmacological standpoints. Pharmacological and therapeutic potentials of chemically-diverse compounds derived from different species of the genus Halimeda are highly promising as antiviral, antimicrobial, cytotoxic, antiproliferative, cardioprotective, anti-inflammatory, anti-osteoarthritic, hypoglycemic, hepatoprotective and neuroprotective agents. This review highlighted the diverse phytochemical and pharmacological properties in different species of the genus Halimeda from 1969 to 2024 based on available literature and also discussed their mechanism of action.