Tube-Like Copper Cobalt Oxide Anchored with Multiwalled Carbon Nanotube Nanocomposite Modified Glassy Carbon Electrode for the Electrochemical Detection of Nilutamide

Abstract

Developing a precise and effective method to detect Nilutamide (NIL) is essential due to its contamination of the environment, which poses significant risks to human health and the biosphere. In this study, we employed a simple hydrothermal technique to create a nanocomposite of CuCo 2 O 4 (copper cobalt oxide) and multi-walled carbon nanotube (MWCNT), which was then anchored onto a glassy carbon electrode for NIL detection. Various spectroscopic techniques were employed to confirm the structure of the nanomaterial, and its electrochemical properties were examined using cyclic voltammetry, differential pulse voltammetry, and electrochemical impedance spectroscopy. The CuCo 2 O 4 /MWCNT nanocomposite-modified electrode exhibited a wide linear detection range from 0.01 to 170 μ M, a high sensitivity of 1.50 μ A μ M −1 cm −2 , a low detection limit of 0.01 μ M, outstanding stability, repeatability, and practical applicability for NIL detection. CuCo 2 O 4 /MWCNT decorated GCE applied for the electrochemical detection of Nilutamide detection. GCE/CuCo 2 O 4 /MWCNT electrode exhibited a wide linear detection range (0.01–170 μ M), a high sensitivity (1.50 μ A μ M −1 cm −2 ), and a low detection limit (0.01 μ M) GCE/CuCo 2 O 4 /MWCNT electrode performed outstanding stability, repeatability, and practical applicability. The practical applicability of the GCE/CuCo 2 O 4 /MWCNT electrode was tested in blood serum and urine samples.