Multiview machine learning using an atlas of cardiac cycle motion

Abstract

A cardiac motion atlas provides a space of reference in which the cardiac motion fields of a cohort of subjects can be directly compared. From such atlases, descriptors can be learned for subsequent diagnosis and characterization of disease. Traditionally, such atlases have been formed from imaging data acquired using a single modality. In this work we propose a framework for building a multimodal cardiac motion atlas from MR and ultrasound data and incorporate a multiview classifier to exploit the complementary information provided by the two modalities. We demonstrate that our novel framework is able to detect non ischemic dilated cardiomyopathy patients from ultrasound data alone, whilst still exploiting the MR based information from the multimodal atlas. We evaluate two different approaches based on multiview learning to implement the classifier and achieve an improvement in classification performance from 77.5% to 83.50% compared to the use of US data without the multimodal atlas.