A Simple Near-Infrared Fluorescent Probe for the Detection of Peroxynitrite

Abstract

Herein, we report the evaluation and synthesis of a reaction based fluorescent probe DCM-Bpin for the detection of peroxynitrite (ONOO−). DCM-Bpin exhibits selective fluorescence off-on response for ONOO− over other reactive oxygen species, including H2O2. Moreover, DCM-Bpin is biocompatible and has been used to visualize exogenous ONOO− in HeLa cells.