Neutralization of influenza a virus by human serum

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Abstract

A linear relationship exists between the quantity of human serum used and the quantity of influenza A virus neutralized. By means of this relationship it is possible to determine the maximum quantity of virus which a given human serum can neutralize. This quantity, the neutralizing capacity, is a fixed value and, unlike the serum dilution end point, is independent of the amount of virus used in the neutralization test. © 1941, Rockefeller University Press., All rights reserved.

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Horsfall, F. L., & Lennette, E. H. (1941). Neutralization of influenza a virus by human serum. Journal of Experimental Medicine, 73(3), 327–333. https://doi.org/10.1084/jem.73.3.327

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