Abstract
We describe a method for mapping quantitative trait loci that allows for locus heterogeneity. A genome-wide linkage analysis of blood pressure was performed using sib-pair data from the Framingham Heart Study. Evidence of linkage was found on four markers (GATA89G08, GATA23D06, GATA14E09, and 049xd2) at a significance level of 0.01. Two of them (GATA14E09 and 049xd2) seem to overlap with linkage signals reported previously, while the other two are not linked to any known signals.
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CITATION STYLE
Yang, X., Wang, K., Huang, J., & Vieland, V. J. (2003). Genome-wide linkage analysis of blood pressure under locus heterogeneity. BMC Genetics, 4 Suppl 1. https://doi.org/10.1186/1471-2156-4-s1-s78
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