Immune response in severe infection: Could life-saving drugs be potentially harmful?

Abstract

Critically ill patients suffer a high rate of nosocomial infection with secondary sepsis being a common cause of death. Usage of antibiotics and catecholamines is often necessary, but it can compromise complex immune response to infection. This review explores influence of these life-saving drugs on host immune response to severe infection. © 2013 Maja Surbatovic et al.