Acute Liver Toxicity due to Efavirenz/Emtricitabine/Tenofovir

  • Patil R
  • Ona M
  • Papafragkakis H
  • et al.
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Abstract

The fixed-dose combination of Efavirenz/Emtricitabine/Tenofovir is a first-line agent for the treatment of HIV; however few cases have reported hepatotoxicity associated with the drug. We report a case of Efavirenz/Emtricitabine/Tenofovir-associated hepatotoxicity presenting mainly with hepatocellular injury characterized by extremely elevated aminotransferase levels, which resolved without acute liver failure or need for liver transplant referral.

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Patil, R., Ona, M. A., Papafragkakis, H., Carey, J., Moshenyat, Y., Alhaddad, A., & Anand, S. (2015). Acute Liver Toxicity due to Efavirenz/Emtricitabine/Tenofovir. Case Reports in Hepatology, 2015, 1–2. https://doi.org/10.1155/2015/280353

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