Meta-analysis: An adolescent in need of evidence and a watchful eye

Abstract

Meta-analysis is a relatively new development in medicine. It is conceptually appealing, summarizing the medical literature in a rigorous manner and providing clinicians with a global picture regarding the merits of interventions. This process can help clinicians choose appropriate, evidence-based management options for their patients. The early enthusiasm for this approach has more recently been called into question. The reliability, and therefore the usefulness, of meta-analysis will improve as more evidence concerning the rigorous ways to conduct and report such studies is developed.