Aortic Dilatation with Bicuspid Aortic Valve

Abstract

To the Editor: In their review on thoracic aortic dilatation associated with bicuspid aortic valve, Verma and Siu (May 15 issue)1 do not mention the increased prevalence of bicuspid aortic valve and its strong association with aortic dilatation and dissection in women with Turner's syndrome.2 This sex-chromosome disorder, which is caused by the loss of all or part of one X chromosome, affects approximately 1 in 2000 live-born females and approximately 80,000 women in the United States. The prevalence of bicuspid aortic valve in Turner's syndrome (approximately 1 in 3) is much greater than that in the general population and . . .