Carcinoma in anal Crohn's disease: Discussion paper

Abstract

In view of the frequent occurrence of chronic anorectal problems with Crohn's disease it is rather surprising that malignant change is not seen more frequently in this area. It is only in recent years that anal malignancy complicating Crohn's disease has been reported. Could this represent a changing disease process with an increasing malignant potential? It seems possible that the perianal region is a site at particular risk of malignant transformation in Crohn's disease.