Effects of Boswellia serrata resin on central nervous system: a mini review

Abstract

Medicinal plants are used for different purposes in traditional medicine. Boswellia serrata (B. serrata) from Burseracea family has been widely used for human medical purposes. This plant known as frankincense or olibanum has a resin with therapeutic properties. The main constituent of this resin is boswellic acid that plays an important role in various fields. From past to present, many studies had been shown that olibanum and its main constituent, boswellic acid, have antiinflammatory, antioxidant, antitumor, anti-arthritic, antimicrobial and anti-carcinogenic effects. In addition, many findings about effects of B. serrata and its ingredients on central nervous system (CNS) are available. Therefore, the aim this study is to review in vivo and in vitro evidence attributed to this plant and its constituents on CNS. Databases including Web of Sciences, Scopus, PubMed and Google Scholar were explored for entries from the beginning of January 2000 until the end of November 2020. Findings reveal that B. serrata and its constituents have neuroprtotective effects and ameliorate learning and memory malfunction. These effects mainly are attributed to the antioxidant and anti-inflammatory properties of this plant.