Clinicopathologic Features of Small Renal Masses Associated with Distant Metastatic Disease

Abstract

Objectives: To assess the clinicopathologic features of small renal masses (≤4 cm) associated with distant metastatic disease. Methods: We identified radical or partial nephrectomies with renal cell carcinomas (RCCs) measuring 4 cm or less in size (pT1a or pT3a) from 2005 to 2015. Clinicopathologic features were compiled. Results: A total of 590 RCCs 4 cm or less were identified, of which 3.9% were associated with distant metastatic RCC. Metastasis was more common in pT3a tumors 4 cm or less than pT1a tumors (19% vs 2.7%; P