Kinetic Studies on the Oxidation of Thiols by Coenzyme PQQ

  • Itoh S
  • Kato N
  • Mure M
  • et al.
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Abstract

Kinetic studies on the oxidation of thiols by coenzyme PQQ are carried out under anaerobic conditions. A bell shaped pH-rate profile having a maximum rate at around pKa of the thiol is observed. The rate-determining step changes between acidic and basic sides of the profile indicating the existence of at least one intermediate in the course of the reaction.

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Itoh, S., Kato, N., Mure, M., & Ohshiro, Y. (1987). Kinetic Studies on the Oxidation of Thiols by Coenzyme PQQ. Bulletin of the Chemical Society of Japan, 60(1), 420–422. https://doi.org/10.1246/bcsj.60.420

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