Computational analysis of Cyclin D1 gene SNPs and association with breast cancer

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Abstract

CCND1 encodes for Cyclin D1 protein and single-nucleotide polymorphisms (SNPs) can modulate its activity. In the present study, the impact of CCND1 SNPs on structure and/or function of Cyclin D1 protein using in silico tools was investigated. Our analysis revealed only one splice site SNP (c.1988+5G

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Aftab, A., Khan, R., Shah, W., Azhar, M., Unar, A., Hussain, H. M. J., & Waqas, A. (2021). Computational analysis of Cyclin D1 gene SNPs and association with breast cancer. Bioscience Reports, 41(1). https://doi.org/10.1042/BSR20202269

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