Coumarins from Bark of Fraxinus japonica and F. mandshurica var. japonica

Abstract

Two biologically active coumarins, scopoletin (1) and isofraxidin (2), along with known coumarins, esculetin (3), fraxetin (4), esculin (5) and fraxin (6), were newly isolated from the bark of Fraxinus japonica Blume (Oleaceae). On the other hand, the bark of F. mandshurica Rupr. var. japonica Maxim Gave only known coumarins, fraxetin (4), fraxinol (7) and mandshurin (8). © 1985, The Pharmaceutical Society of Japan. All rights reserved.