Saponin and Sapogenol. XL.1)Structure of Sophoraflavoside I, a Bisdesmoside of Soyasapogenol B, from Sophorae Radix, the Root of Sophora flavescens AlTON

Abstract

A new bisdesmoside of soyasapogenol B (3), named sophoraflavoside I (2), was isolated together with soyasaponin I (1) from Sophorae Radix (Sophora flavescens Aiton,root). By employing a photochemical cleavage method for the glucuronide linkage in 2 and on the bases of chemical reactions and spectral analyses, the structure of sophoraflavoside I has been determined to be 3-O-[a-L-rhamnopyranosyl(l→ 2)-β-D-galactopyranosyl(l →2)-β-D-glucuronopyranosyl]-22-O-[β-D-glucopyranosyl(l →2)-a-L-arabinopyranosyl]soyasapogenol B (2). © 1985, The Pharmaceutical Society of Japan. All rights reserved.