Beryllium dichloride: Efficient promoter for the addition of organolithiums and organomagnesiums to cyclohexen-2-one

Abstract

Organoberyllium compounds, generated by transmetallation from Grignard and organolithium reagents react with 2-cyclohexenone to give predominantly the adducts resulting from conjugated addition. The chemoselectivity of this reaction was found to be highly dependent upon the nature of organic moiety and of the conditions used.