Lovastatin inhibits its own synthesis in Aspergillus terreus

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Abstract

Lovastatin suppresses its own synthesis in the microfungus Aspergillus terreus. The inhibitory effect was documented by spiking identical batch cultures with pure lovastatin (0, 50, 100 and 250 mg/l) 24 h after initiation from spores.

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Casas López, J. L., Rodríguez Porcel, E. M., Vilches Ferrón, M. A., Sánchez Pérez, J. A., Fernández Sevilla, J. M., & Chisti, Y. (2004). Lovastatin inhibits its own synthesis in Aspergillus terreus. Journal of Industrial Microbiology and Biotechnology, 31(1), 48–50. https://doi.org/10.1007/s10295-004-0108-y

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