Journal ArticleOPEN ACCESS

Successful fractionated undiluted doses of COVID ‐19 vaccine in five cases of suspected allergic reactions to the first dose

  • Rivolta F
  • Camilla C
  • Sangalli A
  • et al.
Clinical Case Reports (2022) 10(10)
DOI: 10.1002/ccr3.6348
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Abstract

After a suspected allergic reaction to first dose of mRNA COVID‐19 vaccine, given the PEG skin tests negativity and tolerance in vivo to PEG containing drugs, five patients were vaccinated with the second dose of Pfizer‐Biontech undergoing a fractional protocol, with antihistamine premedication, without presenting immediate or delayed reactions.Our aim was to strengthen that, after an allergological valuation, a fractionated administration of undiluted vaccine seems to be safe and secure in patients with a suspected previous nonsevere allergic reaction to Pfizer‐BioNTech COVID‐19 vaccine.

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Rivolta, F., Camilla, C., Sangalli, A., Chiei Gallo, A., & Pravettoni, V. (2022). Successful fractionated undiluted doses of COVID ‐19 vaccine in five cases of suspected allergic reactions to the first dose. Clinical Case Reports, 10(10). https://doi.org/10.1002/ccr3.6348

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