Early evoked potentials

Abstract

Investigation of early EP events has yielded a number of correlates of psychopathology and revealed changes with psychoactive drugs that may be pertinent to understanding their central effects. Since the equivalents of early EP events in man can be readily identified in animals, positive results from clinical psychiatric studies can guide focused animal investigations on neurophysiological mechanisms in mental illness. The EP correlates promise to provide neurophysiological models, which could help to bridge the gap between clinical and neurochemical phenomena. Awareness of these possibilities should encourage more intensive psychiatric research on early EP phenomena.