Screening study of potential lead compounds for natural product based fungicides from Juniperus lucayana

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Abstract

Based on structure and detoxification data, chemical transformations of 12-hydroxywiddrol (3) isolated from the wood of Juniperus lucayana were performed leading to hemisynthetic derivatives with improved fungicidal activity against Botrytis cinerea, a pathogenic fungus affecting commercial crops.

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Nuñez, Y. O., Salabarria, I. S., Collado, I. G., & Hernández-Galán, R. (2008). Screening study of potential lead compounds for natural product based fungicides from Juniperus lucayana. Natural Product Communications, 3(4), 469–473. https://doi.org/10.1177/1934578x0800300401

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