Potential adverse effects of statins on muscle

Abstract

Statins are widely used drugs to lower LDL-C and reduce risk of CHD. Statins are associated with the adverse effect of myopathy. Although the incidence of adverse effects is relatively low, the fact that millions of people take statins means cases of myopathy could be seen in any given practice. Physical therapists must be aware of this potential side effect, and the risk factors involved, for the overall safety and quality of life of these patients. Appropriate identification of these muscle symptoms in a patient on statin therapy and consultation with a physician may ultimately allow the symptoms to reverse. A heightened awareness of the potential for statin-associated myopathy coupled with improved patient education about the signs and symptoms of myopathy is recommended to improve the safe use of these beneficial drugs.