The landscape of human cancer proteins targeted by SARS-CoV-2

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Abstract

The mapping of SARS-CoV-2 human protein–protein interactions by Gordon and colleagues revealed druggable targets that are hijacked by the virus. Here, we highlight several oncogenic pathways identified at the host–virus interface of SARS-CoV-2 to enable cancer biologists to apply their knowledge for rapid drug repur-posing to treat COVID-19, and help inform the response to potential long-term complications of the disease.

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Tutuncuoglu, B., Cakir, M., Batra, J., Bouhaddou, M., Eckhardt, M., Gordon, D. E., & Krogan, N. J. (2020). The landscape of human cancer proteins targeted by SARS-CoV-2. Cancer Discovery, 10(7), 916–921. https://doi.org/10.1158/2159-8290.CD-20-0559

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