Quantiferon-gold tuberculosis test cannot detect latent tuberculosis in patients with leprosy

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Abstract

Five of 10 paucibacillary leprosy patients were Quantiferon Gold (Q-G) positive with negative chest X-rays. Forty multibacillary leprosy patients were negative. Reports have shown 100% cross-reactivity of ESAT6 and CFP10 between Mycobacterium leprae and Mycobacterium tuberculosis. The Q-G test cannot detect latent tuberculosis in patients with leprosy.

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Rendini, T., & Levis, W. (2015). Quantiferon-gold tuberculosis test cannot detect latent tuberculosis in patients with leprosy. Clinical Infectious Diseases, 61(9), 1439–1440. https://doi.org/10.1093/cid/civ588

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