Penetration of timolol eye drops into human aqueous humour

Abstract

One to 7 hours after instillation of 0.5% timolol eye drops the aqueous humour aspirated from patients about to have cataract extraction showed concentrations of timolol ranging from 150 ng per 100 mg in the first 1 or 2 hours to 10 ng per 100 mg towards the end of the 7 hours. An exponential decay curve fitted the data well.