An examination of factors effecting systolic blood pressure, diastolic blood pressure, and total cholesterol simultaneously using mixed responses model

Abstract

Background: Hypertension is a risk factor that may lead to development of Atherosclerosis (ATS). Recent studies have emphasized on the importance of high blood pressure and cholesterol on cardiovascular diseases. Objectives: This study aimed to simultaneously examine factors that affect total cholesterol (TC), systolic blood pressure (SBP) and diastolic blood pressure (DBP) using the mixed response model. Methods: This cross-sectional study comprised of 245 participants, hospitalized at Shahid Madani state hospital, Khorramabad-Iran diagnosed with ATS in fall and winter 2014. The method of sampling was convenience sampling and the participants were selected through census of all the patients hospitalized in different cardiac wards, except for angiography. Results: Systolic blood pressure was significantly associated with fasting blood glucose (FBG) (P = 0.001), C - reactive protein (CRP) (P = 0.021), erythrocyte sedimentation rate (ESR) (P = 0.004), and low density lipoprotein-cholesterol (LDL-C) (P = 0.002). In addition, FBG (P=0.002), CRP (P = 0.011) and LDL-C (P = 0.027) levels were significantly associated with DBP. It was revealed that age (P = 0.016), smoking (P = 0.010), triglyceride (TG) (P = 0.001) and FBG (P = 0.021) were significantly associated with TC. Conclusions: Cardiovascular diseases are highly prevalent and there are many risk factors. Therefore, it is necessary to provide proper education on changing life style and preventing the disease.