Retardation of the Development of Diabetes Mellitus in a Murine Model of Type 1 Diabetes (NOD Mouse) Fed Morus alba Leaves.

Abstract

We have examined the protective effect of feeding mulberry (Morus alba) leaves against the development of diabetes mellitus in the NOD mouse, a model of type 1 diabetes. Mulberry leaves supplied at 5% in normal chow significantly retarded the appearance of diabetes in terms of hyperglycemia and polydipsia as markers. The present results suggest that intake of mulberry leaves may be beneficial for preventing and/or retarding the development of type 1 diabetes.