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Spatial proteomics of single cells and organelles on tissue slides using filter-aided expansion proteomics

Nature Communications (2024) 15(1)
DOI: 10.1038/s41467-024-53683-7
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Abstract

Hydrogel-based tissue expansion proteomics represents an emerging spatial proteomics approach. Here, the authors develop the filter-aided expansion proteomics (FAXP) strategy, enabling proteomic analysis of single cells and nuclei in formalin-fixed paraffin-embedded (FFPE) tissue sections.

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Dong, Z., Jiang, W., Wu, C., Chen, T., Chen, J., Ding, X., … Guo, T. (2024). Spatial proteomics of single cells and organelles on tissue slides using filter-aided expansion proteomics. Nature Communications , 15(1). https://doi.org/10.1038/s41467-024-53683-7

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