The Role of Sequestration in G Protein-coupled Receptor Resensitization

  • Krueger K
  • Daaka Y
  • Pitcher J
  • et al.
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Abstract

G protein-coupled receptor kinases phosphorylate the agonist occupied conformation of G protein-coupled receptors in the plasma membrane, leading to their desensitization. Receptor resensitization requires receptor dephosphorylation, a process which is mediated by a

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Krueger, K. M., Daaka, Y., Pitcher, J. A., & Lefkowitz, R. J. (1997). The Role of Sequestration in G Protein-coupled Receptor Resensitization. Journal of Biological Chemistry, 272(1), 5–8. https://doi.org/10.1074/jbc.272.1.5

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