Journal ArticleOPEN ACCESS

SW-163A and B, novel immunosuppressants produced by Streptomyces sp.

Journal of Antibiotics (2001) 54(11) 867-873
DOI: 10.7164/antibiotics.54.867
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Abstract

SW-163A and B, novel immunosuppressants, were isolated from the culture broth of Streptomyces sp. SNA 15896. The molecular formulas of SW-163A and B were determined as C34H42N2O12 and C33H40N2O12 based on the HRFAB-MS analysis, respectively. Both compounds were elucidated to be a large ring ester structure through spectroscopic analyses including various NMR measurements. SW-163A and B showed immunosuppressive and antimicrobial activities in vitro.

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Takahashi, K., Tsuda, E., & Kurosawa, K. (2001). SW-163A and B, novel immunosuppressants produced by Streptomyces sp. Journal of Antibiotics, 54(11), 867–873. https://doi.org/10.7164/antibiotics.54.867

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