Abstract
trans- and cis-Icosyl, docosyl, and tetracosyl p-coumarates, constituents of Artemisia annua L., and their structurally-related compounds were synthesized and evaluated for inhibitory activity on DNA polymerases α and β. Among 30 compounds synthesized, octadecyl trans- and cis-p-coumarates and octadecyl p-hydroxyphenyl-propiolate showed strong inhibitory activity on DNA polymerases α and β. © 2009 Pharmaceutical Society of Japan.
Author supplied keywords
Cite
CITATION STYLE
Nishimura, K., Takenaka, Y., Kishi, M., Tanahashi, T., Yoshida, H., Okuda, C., & Mizushina, Y. (2009). Synthesis and DNA polymerase α and β inhibitory activity of alkyl p-coumarates and related compounds. Chemical and Pharmaceutical Bulletin, 57(5), 476–480. https://doi.org/10.1248/cpb.57.476
Register to see more suggestions
Mendeley helps you to discover research relevant for your work.
