Accidental tenfold overdose of propofol in a 6-month old infant undergoing elective craniosynostosis repair

Abstract

We report a 6-month-old male infant undergoing elective craniosynostosis repair who accidentally received a tenfold dose of propofol over a 4-h operative period. Myocardial dysfunction was observed after nearly 3 h of infusion; this could not solely be explained by the propofol overdose. © 2004 Blackwell Publishing Ltd.