Genetic Basis of Endocrine Regulation of Spermatogenesis

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Abstract

Hormonal regulation contributes significantly to spermatogenesis through interactions between the hypothalamic-pituitary-gonadal axis, testosterone synthesis, Sertoli cell function, androgen receptor, and other hormonal influences, such as estrogen. Congenital or acquired causes of endocrine dysfunction can affect spermatogenesis and male fertility. The purpose of this chapter is to discuss the endocrine regulation of spermatogenesis with consideration of its genetic basis.

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Cheng, J. W., & Ko, E. Y. (2020). Genetic Basis of Endocrine Regulation of Spermatogenesis. In Genetics of Male Infertility: A Case-Based Guide for Clinicians (pp. 57–71). Springer International Publishing. https://doi.org/10.1007/978-3-030-37972-8_4

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