A Study of Next Generation Sequencing Data, Workflow, Application and Platform Comparison

Abstract

DNA sequencing determines the precise order of nucleotides within a DNA molecule. Next generation Sequencing (NGS) is an efficient parallel high throughput DNA Sequencing Technology which revolutionizing the genomic research. Earlier methods that are quite expensive give rise to different sequence comparison techniques. NGS used for faster detection of variants in human genome and give rise to accelerated response to disease detection like cancer, hepatitis etc. In this paper work flow of data analysis part of NGS are clearly discussed. The different NGS platforms, its applications and different sequencing comparison techniques are also mentioned here.