Histological investigation of improvement of mandibular atrophy for application of hydroxyapatite dental implant

Abstract

The purpose of this study was to investigate the possibility of applying the hydroxyapatite dental implant to the atrophic mandible after alveolar ridge augmentation using hydroxyapatite granules. The lower P3, P4 and M1 of 3 mongrel dogs were extracted. At 30 weeks, alveolar ridge augmentation was performed with porous hydroxyapatite granules. Sixteen weeks later, hydroxyapatite dental implants were applied to the area. And 4 weeks later, the specimens were taken out and fixed by 10% formalin alcohol. They were embedded in polyester resin and prepared into undecalcified sections. And the sections were stained with toluidine blue to observe the surrounding tissue of the dental implants histologically under light microscopy. RESULTS: 1) Bone formation was seen in most part of the intergranular spaces. However, in the buccal area, there were some spaces in which bone formation was entirely not observed. 2) At 4 weeks after implantation, almost all of the surface of the hydroxyapatite dental implants was attached to the surrounding osseous tissues. But in some parts of the implant surface, especially the buccal, fibrous connective tissue was seen. 3) These results provide a basis for the technique of hydroxyapatite dental implantation with porous hydroxyapatite granules in the atrophic mandibles after alveolar ridge augmentation.