The binding of fluorophores to proteins depends on the cellular environment

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Abstract

Lighten up! To investigate intracellular binders of myotube-specific probes, a thiol-reactive derivative, CDy2, was prepared. In live cells, the derivative selectively localizes in mitochondria and covalently labels its binding partners. Copyright © 2011 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

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Kim, Y. K., Lee, J. S., Bi, X., Ha, H. H., Ng, S. H., Ahn, Y. H., … Chang, Y. T. (2011). The binding of fluorophores to proteins depends on the cellular environment. Angewandte Chemie - International Edition, 50(12), 2761–2763. https://doi.org/10.1002/anie.201007626

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