Physostigmine reversal of midazolam-induced sedation

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Abstract

We observed three cases of prolonged postoperative somnolence following induction of anesthesia with midazolam. In all instances, sedation was rapidly reversed by physostigmine after other measures to awaken the patients had failed.

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Caldwell, C. B., & Gross, J. B. (1982). Physostigmine reversal of midazolam-induced sedation. Anesthesiology, 57(2), 125–127. https://doi.org/10.1097/00000542-198208000-00011

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