Correlation between growth potential of mouse hepatitis viruses in macrophages and their virulence for mice

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Abstract

Correlation between the virulence of mouse hepatitis virus (MHV) for mice and the growth potential of the virus in peritoneal adherent cells was observed for highly virulent MHV-2 and avirulent MHV-1, JHM, and MHV-S strains. However, this phenomenon was not observed in strain MHV-3, which multiplied to almost the same degree in peritoneal adherent cells from susceptible and resistant mouse strains.

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Taguchi, F., Yamaguchi, R., Makino, S., & Fujiwara, K. (1981). Correlation between growth potential of mouse hepatitis viruses in macrophages and their virulence for mice. Infection and Immunity, 34(3), 1059–1061. https://doi.org/10.1128/iai.34.3.1059-1061.1981

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