Safeguarding the Global Research Cold Chain. In-Country and Transborder Transport of Cryopreserved Biological Specimens

Abstract

The transport of cryopreserved biological products at a consistent temperature of −196°C can present significant challenge to researchers and laboratory personnel that may have little experience in this area. This communication will explore the basic principles for successfully managing the transport of cryogenic shipments both domestically and internationally, examining the need for proper packaging, knowledge of the regulatory environment in the country of destination, and a sound risk management strategy. It will also examine the special circumstances and considerations associated with sending cryopreserved biological samples to emerging nations and how best to safeguard shipments in the face of frail infrastructure, cumbersome regulatory environments, dramatic temperature fluctuations, etc. Finally, it will provide researchers with guidelines on identifying reliable and experienced transport/logistics providers and ensuring that their service capabilities conform to individual shipping needs.