Healing potential of cream containing extract of Sphaeranthus indicus on dermal wounds in Guinea pigs

Abstract

A cream containing ethanolic extract of aerial parts of Sphaeranthus indicus, Linn. (Asteraceae) was evaluated for wound healing activity in guinea pigs. The cream was applied in vivo on the paravertebral area of six excised wounded models once a day for 15 days. The cream significantly enhanced the rate of wound contraction and the period of epithelialization comparable to neomycin. © 2006 Elsevier Ireland Ltd. All rights reserved.